This is a lot of subject Jay!
A number of the bigger, heavier, more expensive poppers (say 150g plus) do have bigger cups than smaller, lighter, less expensive poppers (say under 150g) so they do produce a bigger pop and they will work better in a big sea and, theoretically, they will attract fish from deeper water.
My mate Dave Sharples (a frequent contributor to the forum) insists on using big, heavy, very expensive poppers at least some of the time and believes that the fishing gods will one day reward his efforts with a monster GT. That said, he, I and our mate Terry Smith have caught more and bigger fish from The Musandam (to just under 40kg) on 130g GT Mania. Furthermore, the GT Mania has proved bullet proof against GT of that size and against occasional collisions with cliff faces. The same cannot be said of Dave's more expensive poppers.
The most important thing as far as I am concerned, is to use a set-up that you are comfortable and confident with. If you can handle casting big poppers and playing fish on a Komodo Dragon or Wild Violence type rod and if you believe the fishing conditions warrant that approach, go for it. If not, consider a lighter outfit.
If money is not an issue, I guess the right answer is to have several different popping rods and a really wide selection of poppers, within the bounds of what you can handle in terms of power. Unfortunately, for most of us, money, power or both may be issues!!